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Targeted treatment for chronic lymphocytic leukemia: clinical potential of obinutuzumab

Introduction of targeted agents revolutionized the treatment of chronic lymphocytic leukemia (CLL) in the past decade. Addition of chimeric monoclonal anti-CD20 antibody rituximab to chemotherapy significantly improved efficacy including overall survival (OS) in untreated fit patients; humanized ant...

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Detalhes bibliográficos
Publicado no:Pharmgenomics Pers Med
Autor principal: Smolej, Lukáš
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325625/
https://ncbi.nlm.nih.gov/pubmed/25691812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S55501
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