Physiological role of an endoperoxide in human platelets: hemostatic defect due to platelet cyclo-oxygenase deficiency.

The endoperoxide prostaglandin G2 (PGG2) induced platelet aggregation as well as the platelet release reaction (release of ADP and serotonin) when added to human platelet-rich plasma. Formation of a metabolite of PGG2 [8-(l-hydroxy-3-oxopropyl)-9,12L-dihydroxy-5,10-heptadecadienoic acid] and a lipox...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Malmsten, C, Hamberg, M, Svensson, J, Samuelsson, B
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1975
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432552/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1055417/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.4.1446
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