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Ondansetron Pharmacokinetics in Pregnant Women and Neonates: Towards a New Treatment for Neonatal Abstinence Syndrome

Ondansetron is the drug of choice to prevent nausea in women undergoing cesarean surgery and can be used to prevent neonatal abstinence syndrome (NAS). Pharmacokinetics of ondansetron has not been characterized in pregnant women or in newborns. A nonlinear mixed-effects modeling approach was used to...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Elkomy, Mohammed H., Sultan, Pervez, Carvalho, Brendan, Peltz, Gary, Wu, Manhong, Clavijo, Claudia, Galinkin, Jeffery L., Drover, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325425/
https://ncbi.nlm.nih.gov/pubmed/25670522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.5
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