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Low Mutational Burden of Eight Genes Involved in the MAPK/ERK, PI3K/AKT, and GNAQ/11 Pathways in Female Genital Tract Primary Melanomas

Mucosal melanomas exhibit discrete genetic features compared to cutaneous melanoma. Limited studies on gynecological melanomas revealed significant heterogeneity and low mutational burden. To gain further insight into their genetics and DNA repair efficiency, we systematically investigated the statu...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Pappa, Kalliopi I., Vlachos, George D., Roubelakis, Maria, Vlachos, Dimitrios-Efthymios G., Kalafati, Theodora G., Loutradis, Dimitrios, Anagnou, Nicholas P.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324736/
https://ncbi.nlm.nih.gov/pubmed/25695059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/303791
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