Učitavanje...
Target validation and structure–activity analysis of a series of novel PCNA inhibitors
Proliferating cell nuclear antigen (PCNA) plays an essential role in DNA replication and repair. Tumor cells express high levels of PCNA, identifying it as a potentially ideal target for cancer therapy. Previously, we identified nine compounds termed PCNA inhibitors (PCNA-Is) that bind directly to P...
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| Izdano u: | Pharmacol Res Perspect |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BlackWell Publishing Ltd
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4324689/ https://ncbi.nlm.nih.gov/pubmed/25729582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.115 |
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