Acute small-bowel toxicity during neoadjuvant combined radiochemotherapy in locally advanced rectal cancer: determination of optimal dose-volume cut-off value predicting grade 2–3 diarrhoea

BACKGROUND: Current therapeutic standard for locally advanced rectal cancer is the neoadjuvant radiochemotherapy with total mesorectal excision. Diarrhoea is the main acute side effect, induced by the dose to the small-bowel, frequently leading to a treatment modification. Aim of this study was to a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Radiat Oncol
Hauptverfasser: Reis, Tina, Khazzaka, Edwin, Welzel, Grit, Wenz, Frederik, Hofheinz, Ralf–Dieter, Mai, Sabine
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324657/
https://ncbi.nlm.nih.gov/pubmed/25636703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-015-0336-5
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