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The effect of perhexiline on myocardial protection during coronary artery surgery: a two-centre, randomized, double-blind, placebo-controlled trial

OBJECTIVES: Perhexiline is thought to modulate metabolism by inhibiting mitochondrial carnitine palmitoyltransferase-1, reducing fatty acid uptake and increasing carbohydrate utilization. This study assessed whether preoperative perhexiline improves markers of myocardial protection in patients under...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Eur J Cardiothorac Surg
Päätekijät: Drury, Nigel E., Howell, Neil J., Calvert, Melanie J., Weber, Ralf J.M., Senanayake, Eshan L., Lewis, Michael E., Hyde, Jonathan A.J., Green, David H., Mascaro, Jorge G., Wilson, Ian C., Graham, Timothy R., Rooney, Stephen J., Viant, Mark R., Freemantle, Nick, Frenneaux, Michael P., Pagano, Domenico
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324609/
https://ncbi.nlm.nih.gov/pubmed/24948413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ejcts/ezu238
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