HV1 ACTS AS A SODIUM SENSOR AND PROMOTES SUPEROXIDE PRODUCTION IN MEDULLARY THICK ASCENDING LIMB OF DAHL SALT-SENSITIVE RATS

We previously characterized a H(+) transport pathway in medullary thick ascending limb nephron segments that when activated stimulated the production of superoxide by NAD(P)H oxidase. Importantly, the activity of this pathway was greater in Dahl salt-sensitive rats than salt-resistant (SS.13(BN)) ra...

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Détails bibliographiques
Publié dans:Hypertension
Auteurs principaux: Jin, Chunhua, Sun, Jingping, Stilphen, Carly A., Smith, Susan M. E., Ocasio, Hiram, Bermingham, Brent, Darji, Sandip, Guha, Avirup, Patel, Roshan, Geurts, Aron M., Jacob, Howard J., Lambert, Nevin A., O’Connor, Paul M.
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324599/
https://ncbi.nlm.nih.gov/pubmed/24935944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.03549
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