Genomic Profiling of Intrahepatic Cholangiocarcinoma: Refining Prognosis and Identifying Therapeutic Targets

BACKGROUND: The molecular alterations that drive tumorigenesis in intrahepatic cholangiocarcinoma (ICC) remain poorly defined. We sought to determine the incidence and prognostic significance of mutations associated with ICC among patients undergoing surgical resection. METHODS: Multiplexed mutation...

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Udgivet i:Ann Surg Oncol
Main Authors: Zhu, Andrew X., Borger, Darrell R., Kim, Yuhree, Cosgrove, David, Ejaz, Aslam, Alexandrescu, Sorin, Groeschl, Ryan Thomas, Deshpande, Vikram, Lindberg, James M., Ferrone, Cristina, Sempoux, Christine, Yau, Thomas, Poon, Ronnie, Popescu, Irinel, Bauer, Todd W., Gamblin, T. Clark, Gigot, Jean Francois, Anders, Robert A., Pawlik, Timothy M.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324507/
https://ncbi.nlm.nih.gov/pubmed/24889489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-014-3828-x
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