Clinical Severity of Visceral Leishmaniasis Is Associated with Changes in Immunoglobulin G Fc N-Glycosylation

Visceral leishmaniasis (VL) has a high fatality rate if not treated; nevertheless, the majority of human infections with the causative agent, Leishmania infantum chagasi, are asymptomatic. Although VL patients often present with increased levels of serum immunoglobulins, the contribution of antibodi...

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Udgivet i:mBio
Main Authors: Gardinassi, Luiz Gustavo, Dotz, Viktoria, Hipgrave Ederveen, Agnes, de Almeida, Roque Pacheco, Nery Costa, Carlos Henrique, Costa, Dorcas Lamounier, de Jesus, Amélia Ribeiro, Mayboroda, Oleg A., Garcia, Gustavo Rocha, Wuhrer, Manfred, de Miranda Santos, Isabel Kinney Ferreira
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Microbiology 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324239/
https://ncbi.nlm.nih.gov/pubmed/25467439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01844-14
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