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RNA-directed DNA synthesis by the DNA polymerase of Rous sarcoma virus: structural and functional identification of 4S primer RNA in uninfected cells.

The RNA-directed DNA polymerase of Rous sarcoma virus requires a 4S RNA molecule as primer for the initiation of DNA synthesis on the viral 70S RNA genome. We have now functionally identified primer activity in uninfected cells on the basis of the capacity of cellular 4S RNA to actively participate...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Faras, A J, Dibble, N A
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1975
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432420/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/48251/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.3.859
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