Phenotypic characterization of a Csf1r haploinsufficient mouse model of adult-onset leukodystrophy with axonal spheroids and pigmented glia (ALSP)

Mutations in the colony stimulating factor-1 receptor (CSF1R) that abrogate the expression of the affected allele or lead to the expression of mutant receptor chains devoid of kinase activity have been identified in both familial and sporadic cases of ALSP. To determine the validity of the Csf1r het...

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Dettagli Bibliografici
Pubblicato in:Neurobiol Dis
Autori principali: Chitu, Violeta, Gokhan, Solen, Gulinello, Maria, Branch, Craig A., Patil, Madhuvati, Basu, Ranu, Stoddart, Corrina, Mehler, Mark F., Stanley, E. Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323933/
https://ncbi.nlm.nih.gov/pubmed/25497733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.12.001
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