Relative Roles of CD90 and c‐Kit to the Regenerative Efficacy of Cardiosphere‐Derived Cells in Humans and in a Mouse Model of Myocardial Infarction

BACKGROUND: The regenerative potential of cardiosphere‐derived cells (CDCs) for ischemic heart disease has been demonstrated in mice, rats, pigs, and a recently completed clinical trial (CADUCEUS). CDCs are CD105(+) stromal cells of intrinsic cardiac origin, but the antigenic characteristics of the...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Cheng, Ke, Ibrahim, Ahmed, Hensley, M. Taylor, Shen, Deliang, Sun, Baiming, Middleton, Ryan, Liu, Weixin, Smith, Rachel R., Marbán, Eduardo
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2014
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323830/
https://ncbi.nlm.nih.gov/pubmed/25300435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001260
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