Depletion of B‐Cells With Rituximab Improves Endothelial Function and Reduces Inflammation Among Individuals With Rheumatoid Arthritis

BACKGROUND: Individuals with rheumatoid arthritis (RA) are at increased risk for cardiovascular disease, partly due to systemic inflammation and endothelial dysfunction. B‐cells play an important pathogenic role in the inflammatory process that drives RA disease activity. Rituximab, a chimeric murin...

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Bibliographische Detailangaben
Veröffentlicht in:J Am Heart Assoc
Hauptverfasser: Hsue, Priscilla Y., Scherzer, Rebecca, Grunfeld, Carl, Imboden, John, Wu, Yuaner, del Puerto, Gus, Nitta, Elaine, Shigenaga, Judy, Schnell Heringer, Amanda, Ganz, Peter, Graf, Jonathan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2014
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323827/
https://ncbi.nlm.nih.gov/pubmed/25336464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001267
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