Depletion of B‐Cells With Rituximab Improves Endothelial Function and Reduces Inflammation Among Individuals With Rheumatoid Arthritis

BACKGROUND: Individuals with rheumatoid arthritis (RA) are at increased risk for cardiovascular disease, partly due to systemic inflammation and endothelial dysfunction. B‐cells play an important pathogenic role in the inflammatory process that drives RA disease activity. Rituximab, a chimeric murin...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Hsue, Priscilla Y., Scherzer, Rebecca, Grunfeld, Carl, Imboden, John, Wu, Yuaner, del Puerto, Gus, Nitta, Elaine, Shigenaga, Judy, Schnell Heringer, Amanda, Ganz, Peter, Graf, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323827/
https://ncbi.nlm.nih.gov/pubmed/25336464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.001267
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