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Targeted Release of Tobramycin from a pH-Responsive Grafted Bilayer Challenged with S. aureus

A stimuli-responsive, controlled release bilayer for the prevention of bacterial infection on biomaterials is presented. Drug release is locally controlled by the pH-responsiveness of the bilayer, comprised of an inner poly(acrylic acid) (PAA) monolayer grafted to a biomaterial and cross-linked with...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biomacromolecules
Hauptverfasser: Lee, Hyun-Su, Dastgheyb, Sana S., Hickok, Noreen J., Eckmann, David M., Composto, Russell J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323770/
https://ncbi.nlm.nih.gov/pubmed/25585173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm501751v
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