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Spillover Transmission Is Mediated by the Excitatory GABA Receptor LGC-35 in C. elegans

Under most circumstances, GABA activates chloride-selective channels and thereby inhibits neuronal activity. Here, we identify a GABA receptor in the nematode Caenorhabditis elegans that conducts cations and is therefore excitatory. Expression in Xenopus oocytes demonstrates that LGC-35 is a homopen...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Jobson, Meghan A., Valdez, Chris M., Gardner, Jann, Garcia, L. Rene, Jorgensen, Erik M., Beg, Asim A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323542/
https://ncbi.nlm.nih.gov/pubmed/25673867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4557-14.2015
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