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5-Fluorouracil Chemotherapy of Gastric Cancer Generates Residual Cells with Properties of Cancer Stem Cells

Background: 5-Fluorouracil (5Fu) chemotherapy is the first treatment of choice for advanced gastric cancer (GC), but its effectiveness is limited by drug resistance. Emerging evidence suggests that the existence of cancer stem cells (CSCs) contributes to chemoresistance. The aim of the present study...

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Dettagli Bibliografici
Pubblicato in:Int J Biol Sci
Autori principali: Xu, Zhi-Yuan, Tang, Jia-Ning, Xie, Hua-Xia, Du, Yi-An, Huang, Ling, Yu, Peng-Fei, Cheng, Xiang-Dong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323368/
https://ncbi.nlm.nih.gov/pubmed/25678847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.10248
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