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5-Fluorouracil Chemotherapy of Gastric Cancer Generates Residual Cells with Properties of Cancer Stem Cells

Background: 5-Fluorouracil (5Fu) chemotherapy is the first treatment of choice for advanced gastric cancer (GC), but its effectiveness is limited by drug resistance. Emerging evidence suggests that the existence of cancer stem cells (CSCs) contributes to chemoresistance. The aim of the present study...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Xu, Zhi-Yuan, Tang, Jia-Ning, Xie, Hua-Xia, Du, Yi-An, Huang, Ling, Yu, Peng-Fei, Cheng, Xiang-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323368/
https://ncbi.nlm.nih.gov/pubmed/25678847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.10248
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