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A new suite of tnaA mutants suggests that Escherichia coli tryptophanase is regulated by intracellular sequestration and by occlusion of its active site

BACKGROUND: The Escherichia coli enzyme tryptophanase (TnaA) converts tryptophan to indole, which triggers physiological changes and regulates interactions between bacteria and their mammalian hosts. Tryptophanase production is induced by external tryptophan, but the activity of TnaA is also regulat...

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Detalhes bibliográficos
Publicado no:BMC Microbiol
Main Authors: Li, Gang, Young, Kevin D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323232/
https://ncbi.nlm.nih.gov/pubmed/25650045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-015-0346-3
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