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Deferoxamine attenuates lipopolysaccharide-induced neuroinflammation and memory impairment in mice

BACKGROUND: Neuroinflammation often results in enduring cognitive impairment and is a risk factor for postoperative cognitive dysfunction. There are currently no effective treatments for infection-induced cognitive impairment. Previous studies have shown that the iron chelator deferoxamine (DFO) can...

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Bibliografiske detaljer
Udgivet i:J Neuroinflammation
Main Authors: Zhang, Xiao-Ying, Cao, Jiang-Bei, Zhang, Li-Ming, Li, Yun-Feng, Mi, Wei-Dong
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323121/
https://ncbi.nlm.nih.gov/pubmed/25644393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0238-3
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