NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma

We reported previously that increased expression of aldehyde dehydrogenase 1 (ALDH1) in multiple myeloma (MM) is a marker of tumor-initiating cells (TICs) that is further associated with chromosomal instability (CIN). Here we demonstrate that member A1 of the ALDH1 family of proteins, ALDH1A1, is mo...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Yang, Ye, Zhou, Wen, Xia, Jiliang, Gu, Zhimin, Wendlandt, Erik, Zhan, Xin, Janz, Siegfried, Tricot, Guido, Zhan, Fenghuang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322982/
https://ncbi.nlm.nih.gov/pubmed/25230277
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