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Cytotoxic effect of lapatinib is restricted to human papillomavirus-positive head and neck squamous cell carcinoma cell lines
BACKGROUND: Lapatinib is a dual epidermal growth factor receptor (EGFR) and HER2 inhibitor. Overexpression of these receptors is frequently observed in head and neck squamous cell carcinoma (HNSCC). As growing proportion of HNSCC is characterized by human papillomavirus (HPV) infection, we aimed at...
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發表在: | Onco Targets Ther |
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Main Authors: | , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
Dove Medical Press
2015
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4322874/ https://ncbi.nlm.nih.gov/pubmed/25678800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S68235 |
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