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Cytotoxic effect of lapatinib is restricted to human papillomavirus-positive head and neck squamous cell carcinoma cell lines

BACKGROUND: Lapatinib is a dual epidermal growth factor receptor (EGFR) and HER2 inhibitor. Overexpression of these receptors is frequently observed in head and neck squamous cell carcinoma (HNSCC). As growing proportion of HNSCC is characterized by human papillomavirus (HPV) infection, we aimed at...

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書目詳細資料
發表在:Onco Targets Ther
Main Authors: Fumagalli, Ingrid, Dugue, Delphine, Bibault, Jean Emmanuel, Clémenson, Céline, Vozenin, Marie Catherine, Mondini, Michele, Deutsch, Eric
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322874/
https://ncbi.nlm.nih.gov/pubmed/25678800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S68235
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