Notch1 signaling regulates the epithelial–mesenchymal transition and invasion of breast cancer in a Slug-dependent manner

BACKGROUND: The epithelial–mesenchymal transition (EMT) is crucial for the invasion and metastasis of breast cancer. However, how Notch signaling regulates the EMT process and invasion in breast cancer remains largely unknown. METHODS: The impact of Notch1 silencing by specific shRNAs on the EMT and...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Shao, Shan, Zhao, Xiaoai, Zhang, Xiaojin, Luo, Minna, Zuo, Xiaoxiao, Huang, Shangke, Wang, Ying, Gu, Shanzhi, Zhao, Xinhan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322803/
https://ncbi.nlm.nih.gov/pubmed/25645291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0295-3
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