Insulin-like growth factor I stimulates myofibril development and decreases smooth muscle alpha-actin of adult cardiomyocytes.

Adult rat cardiomyocytes in long-term culture express type 1 insulin-like growth factor (IGF) receptors. In contrast to insulin receptors, type 1 IGF receptors are up-regulated during culturing. IGF-I added to the cells at plating increased granular density and pseudopodia number per cell after 7 da...

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Detalhes bibliográficos
Main Authors: Donath, M Y, Zapf, J, Eppenberger-Eberhardt, M, Froesch, E R, Eppenberger, H M
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC43228/
https://ncbi.nlm.nih.gov/pubmed/8127866
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