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An electrophoretic variant of beta-galactosidase with altered catalytic properties in a patient with GM1 gangliosidosis.

In nine patients with GM1 gangliosidosis, liver ganglioside GM1 beta-galactosidase (EC 3.2.1.23) activity ranged from less than 0.01% to 0.05% of normal. In a tenth patient's liver, much higher activity was found (0.5% of normal). In this patient the residual enzyme had the same molecular weigh...

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Detalhes bibliográficos
Main Authors: Norden, A G, O'Brien, J S
Formato: Artigo
Idioma:Inglês
Publicado em: 1975
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC432279/
https://ncbi.nlm.nih.gov/pubmed/804170
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