The Pupil Light Reflex in Leber's Hereditary Optic Neuropathy: Evidence for Preservation of Melanopsin-Expressing Retinal Ganglion Cells

PURPOSE. To investigate the pupillary light reflex (PLR) of patients with severe loss of vision due to Leber's Hereditary Optic Neuropathy (LHON) in the context of a proposed preservation of melanopsin-expressing retinal ganglion cells (mRGCs). METHODS. Ten LHON patients (7 males; 51.6 ± 14.1 y...

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Published in:Invest Ophthalmol Vis Sci
Main Authors: Moura, Ana Laura A., Nagy, Balázs V., La Morgia, Chiara, Barboni, Piero, Oliveira, André Gustavo Fernandes, Salomão, Solange R., Berezovsky, Adriana, de Moraes-Filho, Milton Nunes, Chicani, Carlos Filipe, Belfort, Rubens, Carelli, Valerio, Sadun, Alfredo A., Hood, Donald C., Ventura, Dora Fix
Format: Artigo
Language:Inglês
Published: The Association for Research in Vision and Ophthalmology 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322722/
https://ncbi.nlm.nih.gov/pubmed/23737476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-11137
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