Topical Treatment with Xiaozheng Zhitong Paste (XZP) Alleviates Bone Destruction and Bone Cancer Pain in a Rat Model of Prostate Cancer-Induced Bone Pain by Modulating the RANKL/RANK/OPG Signaling

To explore the effects and mechanisms of Xiaozheng Zhitong Paste (XZP) on bone cancer pain, Wistar rats were inoculated with vehicle or prostate cancer PC-3 into the tibia bone and treated topically with inert paste, XZP at 15.75, 31.5, or 63 g/kg twice per day for 21 days. Their bone structural dam...

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Dettagli Bibliografici
Pubblicato in:Evid Based Complement Alternat Med
Autori principali: Bao, Yanju, Gao, Yebo, Du, Maobo, Hou, Wei, Yang, Liping, Kong, Xiangying, Zheng, Honggang, Li, Weidong, Hua, Baojin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322667/
https://ncbi.nlm.nih.gov/pubmed/25691907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/215892
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