Mitogenic activity of blood components. I. Thrombin and prothrombin.
When added to a culture medium of resting confluent chick embryo fibroblasts in the absence of serum, thrombin (EC 3.4.21.5) is able to stimulate DNA synthesis 12 hr later and to cause a substantial increase in cell number over a period of 4 days. As compared to thrombin, prothrombin exhibits low mi...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1975
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432255/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1054489/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.1.131 |
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