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Mitogenic activity of blood components. I. Thrombin and prothrombin.

When added to a culture medium of resting confluent chick embryo fibroblasts in the absence of serum, thrombin (EC 3.4.21.5) is able to stimulate DNA synthesis 12 hr later and to cause a substantial increase in cell number over a period of 4 days. As compared to thrombin, prothrombin exhibits low mi...

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Bibliografiske detaljer
Main Authors: Chen, L B, Buchanan, J M
Format: Artigo
Sprog:Inglês
Udgivet: 1975
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC432255/
https://ncbi.nlm.nih.gov/pubmed/1054489
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