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Danger- and pathogen-associated molecular patterns recognition by pattern-recognition receptors and ion channels of the transient receptor potential family triggers the inflammasome activation in immune cells and sensory neurons

An increasing number of studies show that the activation of the innate immune system and inflammatory mechanisms play an important role in the pathogenesis of numerous diseases. The innate immune system is present in almost all multicellular organisms and its activation occurs in response to pathoge...

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Bibliographic Details
Published in:J Neuroinflammation
Main Authors: Santoni, Giorgio, Cardinali, Claudio, Morelli, Maria Beatrice, Santoni, Matteo, Nabissi, Massimo, Amantini, Consuelo
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322456/
https://ncbi.nlm.nih.gov/pubmed/25644504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0239-2
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