ROS inhibitor N-acetyl-l-cysteine antagonizes the activity of proteasome inhibitors

NAC (N-acetyl-l-cysteine) is commonly used to identify and test ROS (reactive oxygen species) inducers, and to inhibit ROS. In the present study, we identified inhibition of proteasome inhibitors as a novel activity of NAC. Both NAC and catalase, another known scavenger of ROS, similarly inhibited R...

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Bibliografiska uppgifter
I publikationen:Biochem J
Huvudupphovsmän: Halasi, Marianna, Wang, Ming, Chavan, Tanmay S., Gaponenko, Vadim, Hay, Nissim, Gartel, Andrei L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322432/
https://ncbi.nlm.nih.gov/pubmed/23772801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20130282
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