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Fibroblast growth factor, but not activin, is a potent activator of mitogen-activated protein kinase in Xenopus explants.

Isolated explants from the animal hemisphere of Xenopus embryos were incubated with Xenopus basic fibroblast growth factor (XbFGF) or human activin A. XbFGF incubation resulted in the rapid activation of mitogen-activated protein kinase (MAPK) and ribosomal S6 protein kinase (pp90rsk) in a dose-depe...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Graves, L M, Northrop, J L, Potts, B C, Krebs, E G, Kimelman, D
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1994
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43223/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7510404/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.5.1662
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