Downregulation of Kinesin Spindle Protein Inhibits Proliferation, Induces Apoptosis and Increases Chemosensitivity in Hepatocellular Carcinoma Cells

Background: Kinesin spindle protein (KSP) plays a critical role in mitosis. Inhibition of KSP function leads to cell cycle arrest at mitosis and ultimately to cell death. The aim of this study was to suppress KSP expression by specific small-interfering RNA (siRNA) in Hep3B cells and evaluate its an...

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Detalhes bibliográficos
Publicado no:Iran Biomed J
Main Authors: Doan, Chinh Chung, Doan, Ngoc Trung, Nguyen, Quang Huy, Nguyen, Minh Hoa, Do, Minh Si, Le, Van Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Pasteur Institute of Iran 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322227/
https://ncbi.nlm.nih.gov/pubmed/25605484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6091/ibj.1386.2014
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