Conversion of incomplete antibodies to direct agglutinins by mild reduction: evidence for segmental flexibility within the Fc fragment of immunoglobulin G.

Reduction of interchain disulfide bonds converted some IgG incomplete antibodies to direct hemagglutinins. This conversion occurred whether antibody was free in solution or bound to the red-cell surface. Reduced antibody permitted to reoxidize in air no longer behaved as a direct agglutinin; reversi...

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Hlavní autoři: Romans, D G, Tilley, C A, Crookston, M C, Falk, R E, Dorrington, K J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1977
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC432207/
https://ncbi.nlm.nih.gov/pubmed/267947
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