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Lack of the ubiquitin-editing enzyme A20 results in loss of hematopoietic stem cell quiescence
A balance between quiescence and proliferation is critical for proper maintenance of the hematopoietic stem cell (HSC) pool. Although a lot is known about hematopoiesis, molecular mechanisms that control HSC quiescence remain largely unknown. The ubiquitin-editing enzyme A20 functions as a central r...
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| Опубликовано в: : | J Exp Med |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4322050/ https://ncbi.nlm.nih.gov/pubmed/25624445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20132544 |
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