Moesin and myosin phosphatase confine neutrophil orientation in a chemotactic gradient

Neutrophils respond to invading bacteria by adopting a polarized morphology, migrating in the correct direction, and engulfing the bacteria. How neutrophils establish and precisely orient this polarity toward pathogens remains unclear. Here we report that in resting neutrophils, the ERM (ezrin, radi...

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Bibliografiset tiedot
Julkaisussa:J Exp Med
Päätekijät: Liu, Xiaowen, Yang, Tao, Suzuki, Koya, Tsukita, Sachiko, Ishii, Masaru, Zhou, Shuping, Wang, Gang, Cao, Luyang, Qian, Feng, Taylor, Shalina, Oh, Myung-Jin, Levitan, Irena, Ye, Richard D., Carnegie, Graeme K., Zhao, Yong, Malik, Asrar B., Xu, Jingsong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322047/
https://ncbi.nlm.nih.gov/pubmed/25601651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20140508
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