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Efficacy of paracetamol on patent ductus arteriosus closure may be dose dependent: evidence from human and murine studies

BACKGROUND: We evaluated the clinical effectiveness of variable courses of paracetamol on patent ductus arteriosus (PDA) closure and examined its effect on the in vitro term and preterm murine ductus arteriosus (DA). METHODS: Neonates received one of the following three paracetamol regimens: short c...

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Detalhes bibliográficos
Publicado no:Pediatr Res
Main Authors: El-Khuffash, Afif, Jain, Amish, Corcoran, David, Shah, Prakesh S., Hooper, Christopher W., Brown, Naoko, Poole, Stanley D., Shelton, Elaine L., Milne, Ginger L., Reese, Jeff, McNamara, Patrick J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321957/
https://ncbi.nlm.nih.gov/pubmed/24941212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2014.82
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