The application of solid-state NMR spectroscopy to study candesartan cilexetil (TCV-116) membrane interactions. Comparative study with the AT1R antagonist drug olmesartan

AT1 receptor (AT1R) antagonists exert their antihypertensive effects by preventing the vasoconstrictive hormone AngII to bind to the AT1 receptor. It has been proposed that these biological effects are mediated through a two-step mechanism reaction. In the first step, they are incorporated in the co...

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Publicado en:Biochim Biophys Acta
Autores principales: Ntountaniotis, Dimitrios, Kellici, Tahsin, Tzakos, Andreas, Kolokotroni, Pinelopi, Tselios, Theodore, Becker-Baldus, Johanna, Glaubitz, Clemens, Lin, Sonyan, Makriyannis, Alexandros, Mavromoustakos, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321718/
https://ncbi.nlm.nih.gov/pubmed/24946142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2014.06.003
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