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Genetic engineering of hematopoietic stem cells to generate invariant natural killer T cells

Invariant natural killer T (iNKT) cells comprise a small population of αβ T lymphocytes. They bridge the innate and adaptive immune systems and mediate strong and rapid responses to many diseases, including cancer, infections, allergies, and autoimmunity. However, the study of iNKT cell biology and...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Smith, Drake J., Liu, Siyuan, Ji, Sunjong, Li, Bo, McLaughlin, Jami, Cheng, Donghui, Witte, Owen N., Yang, Lili
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321292/
https://ncbi.nlm.nih.gov/pubmed/25605948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424877112
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