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MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells

Canonical Wnt signaling plays an important role in development and disease, regulating transcription of target genes and stabilizing many proteins phosphorylated by glycogen synthase kinase 3 (GSK3). We observed that the MiT family of transcription factors, which includes the melanoma oncogene MITF...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Ploper, Diego, Taelman, Vincent F., Robert, Lidia, Perez, Brian S., Titz, Björn, Chen, Hsiao-Wang, Graeber, Thomas G., von Euw, Erika, Ribas, Antoni, De Robertis, Edward M.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321275/
https://ncbi.nlm.nih.gov/pubmed/25605940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424576112
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