Mitochondrial alarmins released by degenerating motor axon terminals activate perisynaptic Schwann cells

An acute and highly reproducible motor axon terminal degeneration followed by complete regeneration is induced by some animal presynaptic neurotoxins, representing an appropriate and controlled system to dissect the molecular mechanisms underlying degeneration and regeneration of peripheral nerve te...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Duregotti, Elisa, Negro, Samuele, Scorzeto, Michele, Zornetta, Irene, Dickinson, Bryan C., Chang, Christopher J., Montecucco, Cesare, Rigoni, Michela
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321248/
https://ncbi.nlm.nih.gov/pubmed/25605902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417108112
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