The Protective Effect of Lacidipine on Myocardial Remodeling Is Mediated by the Suppression in Expression of GPR78 and CHOP in Rats

Lacidipine (LAC) is now widely used for the treatment of hypertension and further can prevent cardiac hypertrophy and remodeling. However, the underlying mechanism has not been fully understood. In this study, we examined the protective effects of LAC on cardiac remodeling in spontaneously hypertens...

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Vydáno v:Evid Based Complement Alternat Med
Hlavní autoři: Ge, Yingxiao, Li, Gang, Liu, Baoxin, Guo, Huixin, Wang, Dongzhi, Jie, Qiqiang, Che, Wenliang, Hou, Lei, Wei, Yidong
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320802/
https://ncbi.nlm.nih.gov/pubmed/25688281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/945076
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