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Evolutionarily emerged G tracts between the polypyrimidine tract and 3′ AG are splicing silencers enriched in genes involved in cancer
BACKGROUND: The 3′ splice site (SS) at the end of pre-mRNA introns has a consensus sequence (Y)(n)NYAG for constitutive splicing of mammalian genes. Deviation from this consensus could change or interrupt the usage of the splice site leading to alternative or aberrant splicing, which could affect no...
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| Wydane w: | BMC Genomics |
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| Główni autorzy: | , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BioMed Central
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4320613/ https://ncbi.nlm.nih.gov/pubmed/25523808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-1143 |
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