Intratumoral heterogeneity in a minority of ovarian low-grade serous carcinomas

BACKGROUND: Ovarian low-grade serous carcinoma (LGSC) has fewer mutations than ovarian high-grade serous carcinoma (HGSC) and a less aggressive clinical course. However, an overwhelming majority of LGSC patients do not respond to conventional chemotherapy resulting in a poor long-term prognosis comp...

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Vydáno v:BMC Cancer
Hlavní autoři: Tone, Alicia A, McConechy, Melissa K, Yang, Winnie, Ding, Jiarui, Yip, Stephen, Kong, Esther, Wong, Kwong-Kwok, Gershenson, David M, Mackay, Helen, Shah, Sohrab, Gilks, Blake, Tinker, Anna V, Clarke, Blaise, McAlpine, Jessica N, Huntsman, David
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320586/
https://ncbi.nlm.nih.gov/pubmed/25523272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-982
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