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The CHEK2 1100delC allelic variant is not present in familial and sporadic breast cancer cases from Moroccan population

PURPOSE: The cell-cycle checkpoint kinase 2 (CHEK2) is an important signal transducer of cellular responses to DNA damage, whose defects has been associated with increased risk for breast cancer. The CHEK2 1100delC mutation has been reported to confer a twofold increased risk of breast cancer among...

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Detalhes bibliográficos
Publicado no:Springerplus
Main Authors: Marouf, Chaymaa, Hajji, Omar, Diakité, Brehima, Tazzite, Amal, Jouhadi, Hassan, Benider, Abdellatif, Nadifi, Sellama
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320163/
https://ncbi.nlm.nih.gov/pubmed/25674498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-014-0778-5
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