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Structure-Inherent Targeting of NIR Fluorophores for Parathyroid and Thyroid Gland Imaging

The typical method for creating targeted contrast agents requires covalent conjugation of separate targeting and fluorophore domains. In this study, we demonstrate that it is possible create tissue-specific near-infrared fluorophores using the inherent chemical structure. Thus, a single compact mole...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Hyun, Hoon, Park, Min Ho, Owens, Eric A., Wada, Hideyuki, Henary, Maged, Handgraaf, Hein J.M., Vahrmeijer, Alexander L., Frangioni, John V., Choi, Hak Soo
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319985/
https://ncbi.nlm.nih.gov/pubmed/25559343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3728
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