Segregation at a locus determining an immunoglobulin genetic marker for the light chain variable region affects inheritance of expression of an idiotype

Previous investigations have demonstrated close genetic linkage between loci governing expression of strain-specific idiotypes and immunoglobulin heavy (H) chain allotype (i.e., the C(H) locus). This linkage is presumed to reflect polymorphism of V(H) genes (or of their expression) linked to the pol...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Laskin, J. A., Gray, A., Nisonoff, A., Klinman, N. R., Gottlieb, P. D.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1977
Soggetti:	Biological Sciences: Immunology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431994/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/412192/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.10.4600
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