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Precursor role of arachidonic acid in release of slow reacting substance from rat basophilic leukemia cells.

The release of slow reacting substance (SRS) from rat basophilic leukemia cells (RBL-1) by the ionophore A23187 (5-10 mug/ml) was stimulated 5-fold by arachidonate and inhibited 78% by 5,8,11,14-eicosatetraynoate (an inhibitor of both fatty acid cyclooxygenase and lipoxygenase). Linoleic acid and li...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Jakschik, B A, Falkenhein, S, Parker, C W
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1977
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431989/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/22078/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.10.4577
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