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Rapid Identification of α-Glucosidase Inhibitors from Phlomis tuberosa by Sepbox Chromatography and Thin-Layer Chromatography Bioautography

Alpha-glucosidase inhibitors currently form an important basis for developing novel drugs for diabetes treatment. In our preliminary tests, the ethyl acetate fraction of Phlomis tuberosa extracts showed significant α-glucosidase inhibitory activity (IC₅₀ = 100 μg/mL). In the present study, a combine...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Yang, Yingbo, Gu, Lihua, Xiao, Ying, Liu, Qing, Hu, Haijun, Wang, Zhengtao, Chen, Kaixian
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319760/
https://ncbi.nlm.nih.gov/pubmed/25658100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116922
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