Regulation of Aryl Hydrocarbon Receptor Interacting Protein (AIP) Protein Expression by MiR-34a in Sporadic Somatotropinomas

INTRODUCTION: Patients with germline AIP mutations or low AIP protein expression have large, invasive somatotroph adenomas and poor response to somatostatin analogues (SSA). METHODS: To study the mechanism of low AIP protein expression 31 sporadic somatotropinomas with low (n = 13) or high (n = 18)...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Dénes, Judit, Kasuki, Leandro, Trivellin, Giampaolo, Colli, Leandro M., Takiya, Christina M., Stiles, Craig E., Barry, Sayka, de Castro, Margaret, Gadelha, Mônica R., Korbonits, Márta
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319742/
https://ncbi.nlm.nih.gov/pubmed/25658813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117107
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