Cephalosporinases associated with outer membrane vesicles released by Bacteroides spp. protect gut pathogens and commensals against β-lactam antibiotics

OBJECTIVES: To identify β-lactamase genes in gut commensal Bacteroides species and to assess the impact of these enzymes, when carried by outer membrane vesicles (OMVs), in protecting enteric pathogens and commensals. METHODS: A deletion mutant of the putative class A β-lactamase gene (locus tag BT_...

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Библиографические подробности
Опубликовано в: :J Antimicrob Chemother
Главные авторы: Stentz, Régis, Horn, Nikki, Cross, Kathryn, Salt, Louise, Brearley, Charles, Livermore, David M., Carding, Simon R.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319488/
https://ncbi.nlm.nih.gov/pubmed/25433011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku466
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